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Diabetes and the Medication “Actos”



Type 2 is a chronic disease whereby the insulin produced by the pancreas is not enough for the body to work effectively. The disease is caused by a combination of environmental and genetic factors, and although a strong genetic predisposition exists, the risk of having the disease is high when the associated factors in the life of the individual are high blood pressure, insufficient physical activity, overweight or obesity, poor diet, and poor body, especially where the extra weight rests on the waist.

At the initial stages, Type 2 can be managed through regular physical activity and healthy eating. However, with time, tablets and insulin injections will be needed, and this will help in reducing the long-term complications related, thus helping to prevent the full effect of the natural progression of the disease.

A Common Disease

Type 2 is the most common among the types of diabetes in existence, as it is found in more than 90% of sufferers. The people having Type 1 or gestational diabetes are usually younger than the ones living with Type 2. However, things are now changing – Type 2 is now becoming popular among other age groups.

The Problem of Type 2 Diabetes

The danger with Type 2 diabetes is that the symptoms of the early stages can exist without the knowledge of the sufferer, which may be the case for many years. It also means that, when diagnosed, many sufferers already show signs of hardening of the arteries and tissue damage to the eyes from this type of diabetes. Another problem with the disease is that it is often inevitable to experience damage to the body. With time, the levels of high glucose can damage the kidneys, the small blood vessels, and nerves of the eyes, and heart, with a predisposition to hardening of the large arteries (atherosclerosis), which may lead to stroke and heart attack.

Dehydration is another problem that the patient faces when suffering from Type 2 diabetes. This is when sugar builds up in the blood, leading to an increase in urination. When glucose is lost by the kidneys through urination, the body will also lose a large amount of water, leading to dehydration. Hyperosmolar nonketotic diabetic coma, or diabetic coma, is another problem. When you are severely dehydrated or become very ill, and you are unable to drink enough water to compensate for the body for the fluid lost, a life-threatening complication may develop.

The Symptoms of Type 2 Diabetes

The symptoms experienced when suffering from Type 2 is are similar to the ones of Type 1. These are some of them:

–        Frequent urination

–        Thirst

–        Tiredness

–        Itching, especially around the genitals, caused by thrush (yeast infection)

–        Weight loss, though not always as in the case of Type 1 diabetes. Being overweight is more common with Type 2.

–        Frequent skin infections, for instance, boils or yeast infections.

–        Feeling dizzy

–        Feeling tired and lethargic

–        Frequent hunger

–        Having cuts that take time to heal

–        Blurred vision

–        Headaches

–        Mood swings

–        Leg cramps

The Use of Actos to Treat Type 2 Diabetes

Actos is a popular drug that is used in treating diabetes. However, according to the Canadian Medical Association Journal, a link exists between bladder cancer and the use of Actos. Many studies showed that the side effects of Actos could include an increase in the risk of bladder cancer, especially in patients who used the drug for a period of at least 12 months. The risk of Actos has made there to be many lawsuits filed against the manufacturer, alleging that no warnings were given to patients concerning the risks involved in the use of Actos.

Prospective pioglitazone Clinical Trial in macrovascular events, or “PROactive”, was a study carried out to show the different risks of Actos. Therefore, it has been banned in Germany and France. In the US, the FDA has instructed that the warning labels must always accompany the drug, and those warnings should be subsequently updated. According to Bloomberg Businessweek, as of December 2011, Takeda, the manufacturer could face more than 10,000 lawsuits.

If you or a loved one have been involved with the drug Actos, please visit to learn how you can get involved with the lawsuit currently taking place.