“Synthetic and Bio-identical Hormones Are the same” –Not!!


Women most of the time are told by their doctors that there is no difference between synthetic hormones and bio – identical hormones. They also advise the discontinuity of the hormones because of the increase in risk of cancer. However, according to articles from the Postgraduate presence, there is a marked distinction between synthetic and bio -identical hormones. In contrast to the mentioned increase in risk of cancer by synthetic progestin (provera) studies suggest that there has been decrease in risk of breast cancer with progesterone.

The article also mentions about natural estrogen hormone estriol.  It says that Estriol and progesterone levels noticeably augment during pregnancy, and during the time period after delivery. This increased exposure to progesterone and estriol during and after pregnancy presents a major long-term reduction in the risk for breast cancer.  If these substances were carcinogenic, it would be expected that pregnancy would raise the risk for breast cancer rather than protect against it.”

From the census reports from 2000, there are around 38 million women who are reaching menopause. For many women, natural is understood as safer option. Hence there is demand for natural products. But the meaning of the word natural is different for the customers and the manufacturers. The manufacture of the natural products is not well regulated. Bio identical hormone therapy is the right term. Bio identical Hormone replacement therapy has become the current topic of research because of its beneficial effects on the wellness and well being. It is also known as BHRT and uses the same chemical structure as the hormones which are present in the human body. It does not have any unpleasant side effects and also do not harm the body.

The word natural should not be confused with the word bio- identical. The molecule shape, make up and structure identical to what is made in the human body makes the ideal key for the body’s receptor sites. Such a compound is bio identical. Synthetic on the other hand these days means artificial, but this concept may not be correct. Synthetic implies which is produced by synthesis or is made.  The hormones are prepared in the laboratory than from the biological organism. Some examples of synthetic hormones are Humulin (insulin) and cortisone (cortisol).

The study related to the increased risk of breast cancer amongst women who opted for hormone replacement is as follows:

  • Firstly synthetic progesterone, Provera was proving to be the problem. When it was taken with an estrogen, that study group showed increased risk, but these women were above 60 years of age.
  • The study group of women below the age of 60 who started taking the same had no risk of breast cancer.
  • Bio identical hormones were not used in any of the study groups, they were just synthetic hormones. Bio identical progesterone has been shown to have anti cancer effects according to some studies.

It is agreed by most researchers that women should no1t hesitate in taking hormone replacement therapy for treating menopause and post menopause problems. Many would think that hormone treatments are risky and affect the health adversely. This is not the case.


Synthetic hormones and bio-identical hormones are not the same though they are both created in a lab.  Bio-identical hormones, like synthetic hormones, are made in a lab, what is not correct is that they are exactly the same.  The difference lies in the molecular structure of the hormones.

Bio identical hormones are not new to science. This is a revelation. In the late 1930’s and early 1940’s Russell Marker found a way to change a chemical compound obtained naturally to same molecular structure as of progesterone in women’s bodies. The synthetic hormones came very late into existence.

As compared to chemically transformed synthetic hormones, bio-identical hormones contain the identical molecular structure as those produced naturally in the women’s body.  As a effect of this, the body “recognizes” these hormones and cooperates with them in the same manner it would interact with the hormones produced in the body’s ovaries. It fits just like a key fits in exactly in the lock.

Bio-identical hormones fit perfectly into the body’s hormone receptors. Once the hormone is in place the body shifts back into balance and all of those cruel symptoms of hormone imbalance begin to drop. Synthetic hormones, on the other hand, have chemically transformed shapes which are not easily recognized by the body. Also, they are not metabolized effectively in the body. They interfere with the normal flow of hormonal function. Also it can lead to harmful side effects.

Correct guidance from your physician or doctor will help in choosing the correct hormone replacement therapy for you and you can seek relief from all the symptoms caused by hormone imbalance, caused by age.

Many physicians and pharmacists will try to convince that the synthetic and bio identical hormones are same, they are not!

Author Bio: Jason Phillips is a well known doctor of his town who is providing hormone replacement therapy. People trust him because of his positive results in most of the cases. He also keeps publishing his researches on new and upcoming medical technology.


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